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THOSE FUNNY DRUG COMBINATIONS

THOSE FUNNY DRUG COMBINATIONS

I usually reserve misgivings for some of the drug combinations that pour into the Nigerian market. For instance, a cough syrup will be labelled to contain a suppressant such as dextromethorphan, a mucolytic such as bromhexin,and an expectorant such as ammonium chloride. It is like trying to put the drug and cough reflexes into confusion because you cannot be suppressing cough and expect to expectorate at thesame time. I stand to be corrected. Even some ethical drug combinations are very funny. Another instance is Combination of glibenclamide and metformin. We all know that individually one should be taken before food and the other after food which brings to question the best time to take the drug. Recently, I came across another combination that gives me cause to worry whether our pharmaceutical importers actually study these formulations before bringing them in not to mention NAFDAC’s apathy. The enzyme Serratiopeptidase was combined with an NSAID. Now, an NSAID is meant to be taken with food to prevent ulceration while the enzyme is to be taken on an empty stomach for efficacy, otherwise it will just end up acting as a digestive enzyme of the content of the stomach . In essence, the drug combination will only offer the benefit of the NSAID and not the benefit of the two drugs if taken with food as claimed by the manufacturers because it is only when the enzyme gets into the systemic circulation will it be able to exert its antinflammatory effects. For this reason, it is usually enteric coated and administered on empty stomach alone.
Most of our products come from India. So, I was happy when I came across this list of banned drug combinations from the Indian health ministry as they lack any additional benefit. Three hundred drug combinations were banned due to lack of prove of combined efficacy. click here to get the comprehensive list. I am sure some of them are parading our drug shelves. This is a wake up call on NAFDAC.
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LOW DOSE ASPIRIN MIGHT NO LONGER BE BENEFICIAL,NEW STUDY SUGGERSTS

LOW DOSE ASPIRIN MIGHT NO LONGER BE BENEFICIAL,NEW STUDY SUGGERSTS

k14271345Daily low-dose aspirin therapy may not

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Doctors’ Group issues Guidelines

Doctors’ Group issues Guidelines

side-effect-pills-250x150The risks of powerful narcotic

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Banned drugs still availabale in Nigerian market

Banned drugs still availabale in Nigerian market

side-effect-pills-250x150It is no longer news that the popular drug

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NAFDAC closes 20 drugs shops in Benue

NAFDAC closes 20 drugs shops in Benue

The National Agency for Food and Drugs Administration and Control has closed down 20 pharmacies and patent medicine shops for stocking and selling fake and

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IT IS IN CAMEROUN WITH NAFDAC NUMBER…IT CAN BE HERE TOO, HELP YOURSELF!!!

IT IS IN CAMEROUN WITH NAFDAC NUMBER…IT CAN BE HERE TOO, HELP YOURSELF!!!

Falsified batches of Coartem recently circulating in Cameroon
Coartem is a fixed dose Artemesinin based combination therapy (ACT) (Artemether 20mg and  Lumefantrine 120mg), used for the treatment of Plasmodium falciparum malaria. The genuine product is  manufactured by Novartis and is a WHO pre-qualified medicine.
On 5 November 2013, Novartis informed WHO of further falsified versions of Coartem recently  circulating

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FOOD POISON:NAFDAC begins awareness

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The National Agency for Food and Drug Administration and Control (NAFDAC) has
warned Nigerians about a toxic substance, Aflatoxins found in foods and feeds such as,

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FALSIFIED BATCHES OF POSTINOR 2 RECENTLY DISCOVERED IN NIGERIA

Background
In late June 2013,a batch of falsified postinor 2 was discovered in Lagos international airport,Nigeria containing

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