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Losing the war against antibiotic resistance

Losing the war against  antibiotic resistance

Tackling antibiotic resistance on only one

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WHO to convene an International Health Regulations Emergency Committee on Zika virus and observed increase in neurological disorders and neonatal malformations

WHO to convene an International Health Regulations Emergency Committee on Zika virus and observed increase in neurological disorders and neonatal malformations

WHO Director-General, Margaret Chan ,

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LASSA FEVER AT A GLANCE

LASSA FEVER AT A GLANCE

Lassa fever is a severe viral disease occurring mostly in

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HAPPY NEW YEAR PEOPLE!!!

HAPPY NEW YEAR PEOPLE!!!

we thank you all our esteem readers, those that called or sent messages to inquire why it is taking so long to resolve, thank you, you are our source of strength. I have sincerely

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World antibiotics awareness week: 10 facts on antimicrobial resistance

This is a call on stakeholders to combat drug resistance
The threat from drug resistance is increasing. There is a need for urgent action; everyone must play a part. The complex problem of drug resistance requires collective action. WHO has developed a draft global action plan to combat antimicrobial resistance which has been submitted to the sixty-eighth World Health Assembly, taking place in May 2015. Governments will be asked to approve the plan and, in doing so, declare their commitment to address this global health threat.
1. What is antimicrobial resistance?
Antimicrobial resistance is the ability of a microorganism (like bacteria, viruses, and some parasites) to stop an antimicrobial (such as antibiotics, antivirals and antimalarials) from working against it. As a result, standard treatments become ineffective, infections persist and may spread to others.
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2. Drug Drug resistance is a global problem
Over the past years, the use and misuse of antimicrobials has increased the number and types of resistant organisms. Consequently many infectious diseases may one day become uncontrollable. With the growth of global trade and travel, resistant microorganisms can spread promptly to any part of the world.image read more

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Pharmaceutical society of Nigeria (PSN): Behold the new sherif is here

Pharmaceutical society of Nigeria (PSN): Behold the new sherif is here

Politics at any level is never devoid of

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Here comes the answer 54…the game

Here comes the answer 54…the game

Here are the answers to our

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Irregularities in hospital pharmacy: PCN moves to curb their excesses

It is no longer news that,over 70%of hospitals in Nigeria do not have qualified pharmacist, but pharmacy services are rendered in such hospitals. Against this backdrop, the Pharmaceutical Council of Nigeria said it had concluded arrangements to declare a state of emergency on hospital pharmacy practice across the country.

The Registrar/Chief Executive, PCN, Elijah Mohammed, represented by its Deputy Director (Pharmacy Practice), Peter Iliya, stated this in Abuja during an event organised by the Pharmaceutical Society of Nigeria, in commemoration of this year’s World Pharmacists Day. read more

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Herbal medicine: from myth to reality

Herbal medicine: from myth to reality

African medical practice,over the years has been shroud in secrecy,sorcery and uncertainty, this,among other reasons are why health professionals had viewed it with a pinch of salt. However, today, the story is changing, African medicine is moving towards evidence-based medicine, says a key player and Director of Pax Herbal Clinic and Research Laboratories (PAXHERBALS), Fr. Anselm Adodo.

This progress, according to Father Adodo, who spoke at the Seventh National Congress of Pax health care providers, which is an association of all distributors, agents and scientists, would make African medicine evidence-based. read more

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Here comes the answer 48…the celecoxib

Here comes the answer 48…the celecoxib

On Monday we looked at the application of celecoxib in post surgical patients with respect to other NSAIDs, we got very lively answers from contributors, but for the records Nonsteroidal anti-inflammatory drugs (NSAIDs) are a
group of structurally unrelated organic acids that have analgesic, anti-inflammatory, and antipyretic properties NSAIDs are inhibitors of the enzyme cyclo-oxygenase, and so directly inhibit the biosynthesis of prostaglandins and thromboxanes from arachidonic acid. There are 2 forms of cyclo-oxygenase (COX), COX-1, which is the constitutive form of the enzyme, and COX-2, which is the form induced in the presence of inflammation. Inhibition of COX-2 is therefore thought to be responsible for at least some of the analgesic, anti-inflammatory, and antipyretic properties of NSAIDs whereas inhibition of COX-1 is thought to produce some of their toxic effects, particularly those on the gastrointestinal tract. Most of the NSAIDs currently available for clinical use inhibit both COX-1 and COX-2, although selective COX-2 inhibitors such as celecoxib are now available.

mechanism of action

mechanism of action


Blood platelets represents the first line of host defence when normal cells are injured,and this platelet aggregation is mediated in part by constitutively expressed cyclo-oxygenase I, when inhibited by non-selectively NSAIDs, as shown in the pictures, it predisposes one to bleeding. However, selective NSAIDs does not inhibit cox1,thus excluding the side effects of bleeding while retaining the analgesic effects of NSAIDs. This is the most probable reason the pharmacist changed the take-home drugs to celecoxib.
If you missed the question, click THE celecoxib
We appreciate the responses from Chinonye and obiyindo, as well as Pharmacist Audu,who wrote in for us to learn more,you guys rock!!!
Join us every Monday for can you deliver series,and Fridays for here comes the answer series,we expect your replies to the questions and your criticisms to our answers. If you have any experience as a pharmacist, a medical doctor,a nurse, scientist,physiotherapist etc that you think will help improve learning ,you can email them to us at ugwulekecc@gmail.com for publication
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follow on twitter @futurerxdream or @ugwuleke
BBM channel C002D3B6D read more

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can you deliver 46..the ngo out-station

can you deliver 46..the ngo out-station

Chima has just received a probational appointment with one of the

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WE MUST NOT ALLOW PHARMACY PRACTICE GO THE WAY OF MEDICAL PRACTICE

WE MUST NOT ALLOW PHARMACY PRACTICE GO THE WAY OF MEDICAL PRACTICE

WE MUST NOT ALLOW PHARMACY PRACTICE GO THE WAY OF MEDICAL PRACTICEIt has become very obvious that for the past few years, the status of the pharmacist has been justifiably

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We Thought You Should KnowKnow…I.M Injections

We Thought You Should KnowKnow…I.M Injections

Muscles with thick bellies are commonly used for intramuscular (I.m) injections. Since drugs injected into these muscles are absorbed into the bloodstream gradually, it is safe to administer relatively large doses (up to 5ml) that could be dangerous or even fatal if injected directly into the bloodstream. I.m injections also causes less tissue irritation than subcutaneous injections.
Knowledge of the subsurface anatomy is necessary to avoid damaging nerves or to avoid injecting directly into the blood vessels. Anatomical knowledge also enables a clinician to position a patient so that the muscle is relaxedrelaxed, making the injection less painful.
Amounts up to 2MLAs are injected int

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Fighting TB – South Africa’s ‘Insidious Epidemic’

Fighting TB – South Africa’s ‘Insidious Epidemic’

SOUTH AFRICASouth Africa stands at the center of a global

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We thought you should know 3… WHY DO WOMEN UNDERGO MENOPAUSE

We thought you should know 3…  WHY DO WOMEN UNDERGO MENOPAUSE

There has been considerable speculation why women do not remain fertile till the end of their lives, as men do. Some theorist argue that menopause served a biological purpose for our prehistoric foremothers. Human off springs take a long time to rear. Beyond a certain point, the frailties of age, make it unlikely that a woman could rear another infant to maturity or even survive the stress of pregnancy. She might do better in the long run to become infertile and finish rearing her last child instead becoming pregnant for another one. In this view, menopause was biologically advant

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Can You Deliver 32..The Contraceptive

Can You Deliver 32..The Contraceptive

Pharmacist good morning, good morning he replied a jaw dropping pretty lady, please, I came to see you…sorry I did not allow you time to relax, she apologized. It is okay, replied the pharmacist, so what can we do for you? He asked. I will like to have a private discussion with you. Okay, ushering her into his office, please make yourself comfortable, he urged her, she nodded in agreement and eased herself into the visitor’s chair.
After a brief silence, in what looks like a prayer, he apologized for the delay and asked her to go on with her complain.
Doctor…sorry, pharmacist, I just have to be blunt. Yesterday I was having sex with my fiancé, and in the process, the condom b

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Here Comes The Answer 31…The Trust

Here Comes The Answer 31…The Trust

Well madam, this other prescription withmetronidazole400mg tds,ciprofloxacine 500mg bd and clotrimazole insert 1 nocte might have to do with an infection she had complained of, to her doctor or pharmacist. However, this one with orlistat 120mg tid,is where i need to make all necessary input as regards her complain. the flatulence is due to the orlistat, this drug is associated with gastrointestinal disturbances, including faecal urgency and incontinence, flatulence, and fatty stools or discharge, are the most frequently reported adverse effects during tr

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Pharmacist less likely to divorce than physicians and others

Pharmacist less likely to divorce than physicians and others

Pharmacist less likely to divorce than physiciansCompared with other health care professionals,

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Daily Pharmacist’sLife…Castor oil for pregnancy

Daily Pharmacist’sLife…Castor oil for pregnancy

castor A client to my office yesterday evening, heavily pregnant. She demanded to see the pharmacist, I told her I was the pharmacist. I want to

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Statins Linked To Diabetes

Statins Linked To Diabetes

Even healthy adults taking statins are more likely to develop diabetes.

A recent study published in the Journal of General Internal Medicine evaluated 3982 Tricare beneficiaries who were taking statins and 21,988 peers in the military health system who were not.

Using 42 baseline characteristics, the researchers matched 3351 statin users to 3351 nonusers and then examined the incidence of diabetes, diabetic complications, and obesity in both groups. At baseline, all study subjects had no cardiovascular disease, diabetes, or other life-limiting chronic disease.

In addition to seeing a strong association between new-onset diabetes and statin use, those taking statins also had a 250% greater likelihood of developing diabetes with complications than their counterpa

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