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Can YOU Deliver 72…The Sustain Release

Can YOU Deliver 72…The Sustain Release

This is the 72nd edition of our “can you deliver series”, and in the past year, I have received some mails like this one.
Good day senior colleague, I want to appreciate you for what you guys have been doing with the can you deliver series, but, I would like it, if you guys can also discuss cases in other areas of pharmacy practice besides community and hospital setting
Our reply
Thank you for the observation,the truth remains that what we writing are based purely on what we see daily in the community setting,people who have written to us are mostly community and sometimes hospital pharmacists. However, in response to this,we will  begin our search for industrial colleagues.
Today, see what we have got.
There was this interview I attended for a company that wants to import certain drugs, I was to register and work as a superintendents, I tell you , it was a different ball game to what we all know and do, like register a premise and all. Before I went for that interview, I was told they want to bring in sustained released diclofenac, so,normal thing,I jack everything on sustained release I could lay my hands on, “to better the company”. When I arrived on the day of interview,we were two, facing ourselves on either end of a mini conference table, with our “ogas”to be sitting in between. The other guy was told that what they wanted to bring in was just ordinary diclo,not sustain, I was asked to give the guy 5 reasons why we should NOT bring in SUSTAINED RELEASE,do you get it?,why we should not bring it in,recall I was told that is what we will bring in, The other guys was was also told to give me 5 reasons we should not bring in ordinary diclofenac, and we were informed that whoever convinces the other would be taken. read more

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Counterfeit drugs: NAFDAC intercepts Kano bound truck

Counterfeit drugs: NAFDAC intercepts Kano bound truck

As the war against counterfeit drugs rages, thisday reports that

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Here Comes The Answer 71…Paracetamol Syrup vs Drop

Here Comes The Answer 71…Paracetamol Syrup vs Drop

I read through some of the most interesting comments on social media, as regards the 71st edition of our CAN YOU DELIVER series.Sincerely, I learnt one or two things.
The answer to that question is very simple to explain,and it is straight forward.
In this part of the world,most of our paracetamol syrup comes in strength of 125mg/5ml, while the drop comes in 100mg/ml. Therefore, when an a concerned parents who has be wrongly thought in the clinic gets to the pharmacy, the cobwebs should be cleaned,even if they refused and insist on buying the syrup for their infant (as some do), at least, you have explained the rationale for your decision.
A typical scenario is what we saw on the that 71st question,in such cases most times, the buyer feels since syrup is ”bigger” than drop,then it is “stronger” that it. Most times, they were advised (wrongly) to give 2.5mls of the syrup as against 1ml of the drop. Now let’s explain. Madam, if you withdraw 1ml of this drop, you will get 100mg of this paracetamol, but if you withdraw 5mls of this syrup,you will get 125mg of paracetamol, therefore,if you withdraw 2.5mls of this syrup, you will get 62.5mg of paracetamol, so,as you can see, 100mg and 62.5mg, which is more and also, with dropper,it is easier to administer. Most of them will be like…ahhh, is that so,..yes ma,that is so.
What did I learn? One of the greatest community pharmacist I know, Pharmacist Wale,posted something,peharps of international standard in response to to this question,and I quote.
Dosage information FOR PARACETAMOL/ACETAMINOPHEN ( para-acetyl amino Phenol)
There are seven age bands for dosage, as outlined below: read more

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Buhari Appoints new Directors

Buhari Appoints new Directors

The president, Federal republic of Nigeria,Mohammadu Buharia has approved the appointment of heads of 5 health institutions
The heads are; the Centre for Disease Control, National Agency for the Control of Aids, the Nigerian Institute for Medical Research.

And the National Primary Health Care Development Agency and National Health Insurance Scheme.

NIMR – Prof Babatunde Salami; NACA – Dr Sani Aliyu; NHIS – Prof Usman Yusuf; NPHCDA – Prof Echezona Ezeanolue and
CDC – Dr Chikwe Andreas Ihekweazu. read more

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World Hepatitis Day 2016…No hep!

World Hepatitis Day 2016…No hep!

That was yesterday but the message should remain in our hearts. To WHO we turn,

World Hepatitis Day, 28 July 2016 is an opportunity to step up national and international efforts on hepatitis and urge partners and Member States to support the roll-out of the first Global Health Sector Strategy on viral hepatitis for 2016–2021, which was approved during the Sixty-ninth World Health Assembly in May 2016.

The new strategy introduces the first-ever global targets for viral hepatitis. These include a 30% reduction in new cases of hepatitis B and C, and a 10% reduction in mortality by 2020. read more

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Buhari sacks all directors in the ministry of health

Buhari sacks all directors in the ministry of health

President Muhammadu Buhari yesterday sacked all

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HIV Treatment:New Antibiotics Continues to Show Promise.

HIV Treatment:New Antibiotics Continues to Show Promise.

Researchers world over has,in recent years made tremendous progress to develop treatment options for HIV patients,today, anti-retrovirals remains the mainstay of managing the disease, the permanent cure has remained elusive.

Now, Rockefeller scientists report that they are one step closer to an alternative treatment that utilizes antibodies. This therapy has the potential for long-acting effects and would allow for less frequent dosing.

Recently published in Nature, the findings suggest that an antibody called 3BNC117 can effectively delay the virus from rebounding in patients who temporarily suspended their anti-retroviral medications, currently the standard treatment for HIV. read more

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Salmonella Protein Reduces Drug Resistance in Tumors

Salmonella Protein Reduces Drug Resistance in Tumors

"It is fascinating to think that this discovery has incredible clinical potential for treating certain drug resistant cancers. On the strength of

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Can you deliver 71…Syrup vs Drop

Can you deliver  71…Syrup vs Drop

The discussion between drop and syrup is nothing new to a practicing communtypharmacist.
This friend of mine had just finished his service and luckily got a superintendent job, he resumed and of course assumed all responsibilities with minimal experience at his disposal. With over one year of community practice experience, I am in a better position to put him through, so once in a while I go there to lend him a helping hand.
On this very day, as I stepped into the pharmacy, he rushed me..Pharm, please can you help me explain this to this lady, she wanted to buy paracetamol for her 4 months child,I sold the drop to her, she just brought it back and started insulting me, that I do not know what I am doing, that how could I give a drop for a four months old baby,knowing fully well that the syrup was stronger and more appropriately,I am really angry now,I am just trying hard not show it. (moving closer to the lady and in a lower tone) He said, Senior colleague, how do I best explain to this lady that paracetamol is paracetamol irrespective of the dosage form, before I could alter a word, the lady said. Sorry o, “senior colleague” did you hear what he just said, please how is 1ml of paracetamol in drop same as 2.5ml in syrup, because I was told in general that drop is not good for my baby,that drop is meant for baby like 1-3 months,my baby is 5 months!!!.Please convince me our senior colleague.
Join us every Monday to Tuesday for can you deliver series,and Friday through Saturdays for here comes the answer series,we expect your replies to the questions and your criticisms to our answers.
If you have any experience as a pharmacist, a medical doctor,a nurse, scientist,physiotherapist etc that you think will help improve learning ,you can email them to us at ugwulekecc@gmail.com for publication. read more

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Males with high Paracetamol level in the system may not conceive

Males with high level of paracetamol in the system could take longer to

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Here comes the answer 70th! The multivitamin Challenge

Here comes the answer 70th! The multivitamin Challenge

Most times multivitamins are given to supplement nutritional deficiencies in undernourished patients. It goes without saying that healthy people only experience a placebo effect when these supplements are taken. Multivitamins in the market contain the basic vitamin requirements with one or two variations. It is in this variations we based our question because that is what distinguishes a well thought-out multivitamin preparation from a “join the fray” one.

Both preparations in our case study were rich in composition like Evans said but the pharmacist’s interest in the second formulation was as a result of this. Aside from its own benefit, Boron is known to enhance the absorption of calcium and magnesium. Biotin also does same for B vitamin absorption just as vitamin C for Iron. So, for one who is really malnourished, these contents will help to maximise the utility of the multivitamin. read more

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Suppressive Antiretroviral Treatment Prevents HIV Transmission – Study

Suppressive Antiretroviral Treatment Prevents HIV Transmission – Study

couples had sex regularly without using a condom. They have now been

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U.S. Senate Committee on Appropriations Approves $745m To Fight Malaria In 2017

U.S. Senate Committee on Appropriations Approves $745m To Fight Malaria In 2017

Momentum continues to build in the global fight against malaria. Just this weekend, a major increase in funding from the U.S. Senate, significant Global Fund commitments from France and Italy, and a strong statement from President Obama demonstrated that U.S. and global leaders remain committed to ending the deadly disease.
The U.S. Senate Committee on Appropriations approved $745 million to fight malaria in Fiscal Year (FY) 2017, weekend. This commitment to malaria in the State, Foreign Operations, and Related Programs appropriations bill represents a $71 million increase over the FY 2016 funding level. The bill also includes $1.35 billion for the Global Fund to Fight AIDS, Tuberculosis, and Malaria. It now awaits consideration by the full Senate.
In his remarks to Canada’s House of Commons, President Barack Obama said: “With our commitment to new sustainable development goals, we have the chance to end the outrage of extreme poverty. We can banish the scourge of malaria.” This echoes the call to action that President Obama made both before the United Nations General Assembly in September 2015 and during his final State of the Union address in January.
“Malaria No More applauds the Senate Appropriations Committee and President Obama for prioritizing critical resources and keeping malaria high on the global agenda,” said Josh Blumenfeld, Managing Director of Global Policy and Advocacy at Malaria No More. “This is exactly the commitment and leadership that are needed to save thousands of lives, but we still have a long way to go.”
The world has made tremendous progress in the fight against malaria during the past 15 years. Since 2000, concerted global efforts have contributed to a 60 percent reduction in the rate of deaths from malaria and have saved 6.2 million lives. At the same time, malaria remains a leading cause of death and illness in half of the world’s population. Approximately 90 per cent of malaria cases and deaths still occur in sub-Saharan Africa. In Southeast Asia, the specter of drug resistance remains a serious threat.
Earlier, the Government of France pledged $1.19 billion over the next three years to the Global Fund – a clear reflection of its commitment in the fight to end malaria. The Government of Italy pledged $144 million, which represents a 30 per cent increase over its 2014-2016 contribution to the Global Fund.
“Such strong commitments from the U.S., France and Italy bring us closer to the attainable goal of raising $13 billion at the Global Fund Replenishment Conference in Montreal in September,” said Blumenfeld. “These critical resources will help cut malaria cases in Africa in half by 2020 – from nearly 250 million to less than 125 million – saving lives and ending the needless suffering of millions of people.”
……………………………………………………..Chioma umehi
SOURCE: Thisday read more

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Heart Failure: Many drugs can cause or worsen it.

Heart Failure: Many drugs can cause or worsen it.

Commonly used medications and nutritional supplements may cause or worsen heart failure (HF), according to the first scientific statement from the American Heart Association to provide guidance on avoiding drug–drug or drug–condition interactions for people with HF (Circulation 2016 Jul 11. [Epub ahead of print]).
The statement provides comprehensive information about specific drugs and supplements that may have serious unintended consequences for HF patients.

Patients with HF have, on average, five or more separate medical conditions and take seven or more prescription medications daily, often prescribed by different health care providers. According to the statement, medications can cause problems in several ways: being toxic to heart muscle cells or changing how the heart muscle contracts; interacting with medications used to treat HF so that some of their benefits are lost; and containing more sodium than advised for patients with HF.
“Since many of the drugs heart failure patients are taking are prescribed for conditions such as cancer, neurological conditions or infections, it is crucial but difficult for health care providers to reconcile whether a medication is interacting with heart failure drugs or making heart failure worse,” said Robert L. Page II, PharmD, MSPH, the chair of the writing committee for the new scientific statement. read more

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YOUNG PHARMACISTS NIGERIA,SHINE YOUR EYES!

YOUNG PHARMACISTS NIGERIA,SHINE YOUR EYES!

Meanwhile the the doctor telling you thar they have started residency in pharmacology,did you ask him if that will accord them a slot to be registered in pcn as pharmacists? These are issues we must be well informed on. Cos we all might be the only mobile billboard, that pharmacy practice in Nigeria will ever have.Their proffession is saturated and unemployment,hunger and confusion is taking over. So any available channel is a way out. Even If it’s to do residency in zoology. Some are begging to open pharmacy shops.In fetha,ebonyi state,there is a pharmcology dept headed and run by doctors alone. That’s ok by me. But what is their role?truth is that its just an office created to employ more doctors. They are often sitting around doing absolutely nothing. But if support is not given to the pharmacy dept of such institution,that pharmacology dept will one day start claiming relevance.The consultant pathologists/heamatologists vs lab science war got to this point cos it started at a time when there existed gross ignorance in the ministry of health In Nigeria.so they shouldn’t hope same will happen to pharmacy vs consultant pharmacologist.  Today every arm is awake and watchful. No mago mago Can occur like in the days of Dr. Ransom kuti,who by the way is the cause of all our problems. He brought about this division by favouring the Dr so much.I dont blame him cos when Adelusi,a pharmacist, was there as health minister,he was upright and straight. He never gave us undue advantages. As it stands,undue advantage, is the new way out. Whilst your doctor friend is glorying in the new residency in pharmacology,my dear, hope he is aware we run a residency now too?Most pharmacists will leave school and wont enrol for the west African post graduate college of pharmacists.why? That’s sad. All things being equal if by Nov I graduate from Wapcp as a clinical oncologist,does that make me a medical Dr?no!it only makes me a pharmacist that is a consultant in clinical oncology…more knowledge about that area of practice to give the right advice and better collaboration. Will I suddenly start doing surgery,chemotherapy or radiotherapy on cancer patients?no! My consultation will still be limited to the issues that are drug based in cancer. So a doctor doing residency in pharmacology will only be stupid to think he is suddenly a pharmacist.Whilst they have not recovered from Pharm. D,we stepped up to residency too. They should better upgrade from M.B.B.S to MD first. They are the only ones in the world still graduating doctors as mbbs holders. Lols. Bachelor of medicine,bachelor of surgery. *scoufsNigerians call them doctors by default cos there is no doctor in the mbbs certificate. I am glad with community pharmacists,their new layouts,especially those practicing pharm. Care. They are changing our image in the Nigerian society. Its the hospital pharmacists that baffle me. Majorly layed back and accepting of any rubbish….By Pharmacist .Ene Jane Francis-ani read more

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Family Planning: Pharm Billy Shoaga Norminated by John Hopkins

Family Planning: Pharm Billy Shoaga Norminated by John Hopkins

A Nigerian, Pharmacist Billy Shoaga has been nominated by John Hopkins for an award in family planning

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Can you deliver 70th: The multivitamin

Can you deliver 70th: The multivitamin

The room is silent, my boss trust my judgemen, the reps are all ears, what I say must be backed with accessible facts, if you were in my shoes, what would it be?

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Court dismisses patent medicine dealers’ case against PCN

Court dismisses patent medicine dealers’ case against PCN

The court held that the PCN Act 1992 empowers the PCN to

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Giving Tramadol? Check That Glucose Reading!

Giving Tramadol? Check That Glucose Reading!

There have been reports of patients taking tramadol for pain requiring hospitalization because of these

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Increasing need for repellent

Increasing need for repellent

Use of insect repellents is strongly recommended by the CDC and the EPA to prevent Zika virus infection1, and other mosquito- and tickborne diseases. Mosquitoes can transmit chikungunya, dengue, West Nile, and yellow fever viruses, and malaria. Ticks can transmit Lyme disease and rickettsial diseases such as Rocky Mountain spotted fever.

DEET — The topical insect

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