Home / Here comes the answer / Here Comes The Answer 39..The Prescription
Here Comes The Answer 39..The Prescription

Here Comes The Answer 39..The Prescription

Here Comes The Answer..32; The ContracepetiveOn Monday we took a look at a prescription and tried to get your opinions on this, before today being Friday. Anyway this is what we think.
Many of the adverse effects of ACE inhibitors relate to their pharmacological action and all therefore have a similar spectrum of adverse effects. ACE inhibitors induce a bothersome dry cough,it is usually not dose related, occurs more frequently in women than in men, usually develops 1 week and 6months after initiation of therapy. This adverse effect may be mediated by by accumulation in the lungs of bradykinin,substance P and/or prostaglandin.
looking at the prescriptions again, it is clear that cough is most probably due to the lisinopril. Now what options do we have, from pharmaceutical,therapeutic and economic viewpoints.
1.we can sell the drugs to the patient, keep our knowledge and keep rhinathiol money in our pocket,at least it is not o/s
2.we can send the patient back to the prescriber, to review the prescription, by so doing we cost the patient more money (T.fare,or fuel if he/she is mobile),but save his life, educate the prescriber and prevent further spending.However, the prscriber might insist on his own (if you read my meaning), and send the patient elsewhere,thereby keeping his/her ego and keeping our knowledge as well,meanwhile,we lost patient and money!!!
3. we can change the ACEI to ARB,tell the patient not to buy the rhinathiol, because he/she does not need it, and encourage him/her to see his/her prescriber and explain what the pharmacist said,a good prscriber would be your friend at once. Or better still manage the cough,how??..see below
NOTE: ACEIs induced cough can be managed with aspirin or iron supplements or thromboxane antagonist…do you know that before…i guess not,bookmark and visit us, we will learn together.
There are some lovely comments on this i saw on face book, i don’t why you do not want to put it here o,any way..
if you missed the question click the prescription
Join us every Monday for can you deliver series,and Fridays for here comes the answer series,we expect your replies to the questions and your criticisms to our answers. If you have any experience as a pharmacist, a medical doctor,a nurse, scientist,physiotherapist etc that you think will help improve learning ,you can email them to us at ugwulekecc@gmail.com for publication
Do not forget to like our page on facebook,
follow on twitter @futurerxdream or @ugwuleke
BBM channel C002D3B6D

NOTE; Every first and last fridays of the month would be interns focused questions.
You can see
Goodman and Gilman, pharmacological basis of therapeutics,11th edition page 808
Martindale, the complete drug reference 36the edition!Page 1193

Scroll To Top