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Here Comes The Answer 74…The thyroid (levothyroxine) drug

Here Comes The Answer 74…The thyroid (levothyroxine) drug

There basically two types of thyroid drugs,based on what is happening to the thyroid gland
The thyroid gland facilitates normal growth and maturation by maintaining a level of metabolism in the tissues that is optimal for their normalfunction. The two major thyroid hormones are triiodothyronine (T3; the most active form) and thyroxine (T4). Inadequate secretion of thyroid hormone (hypothyroidism) results in bradycardia, poor resistance to cold,and mental and physical slowing. In children, this can cause mental retardation and dwarfim. In contrast, excess secretion of thyroid hormones (hyperthyroidism) can cause tachycardia and cardiac arrhythmias, body wasting, nervousness, tremor, and heat intolerance

Hypothyroidism usually results from autoimmune destruction of the gland or the peroxidase and is diagnosed by elevated TSH. Levothyroxine (T4) is preferred over T3 (liothyronine) or T3/T4 combination products (liotrix) for the treatment of hypothyroidism. It is better tolerated than T3 preparations and has a longer half-life. Levothyroxine is dosed once daily, and steady state is achieved in 6 to 8 weeks. Toxicity is
directly related to T4 levels and manifests as nervousness, palpitations and tachycardia, heat intolerance, and unexplained weight loss.
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